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The effects were compared to the alpha(2)-agonist m-trifluoroethylphenyldimethylmethoxamine, to the antagonist prazosin and to the calcium-channel antagonist nifedipine. For the determination of hemodynamic effects, the following parameters were measured: mean blood pressure (MAP), left ventricular systolic blood pressure (LVSP), left ventricular end diastolic pressure (LVEDP), heart rate (HR), left ventricular (LV) dP/dtmax, LV dP/dtmin, RV dP/dtmax, and RV dP/dtmin. All sesquiterpene lactones examined caused hypotension, bradycardia and an increase in RV dP/dtmax and RV dP/dtmin. The hypotensive effect was antagonized by prazosin whereas the increase in RV dP/dtmax and RV dP/dtmin was antagonized by nifedipine. Compared to m-trifluoroethylphenyldimethylmethoxamine the sesquiterpene lactones did not reduce HR (in contrast to m-trifluoroethylphenyldimethylmethoxamine), increased LVSP (in contrast to m-trifluoroethylphenyldimethylmethoxamine) and caused no increase in LVEDP, a characteristic feature of alpha(2)-agonists. The sesquiterpene lactones used did not show antagonist properties towards alpha(1)-adrenoreceptors or alpha(1)- Lovebirds Theme Free Download Lovebirds Theme is a pack of 5 high resolution love birds desktop images. You may use these love birds for your Valentine's Day, your favorite gifts, personal photos, social posts or any other occasion that calls for a dash of romance and love. With these bright and cheerful lovebirds you'll be able to get that special moment in your life where you can show the world what you feel. 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